Risk Categorization Predicts Disability in Pain Using Web-based Modules

Abstract

We sought to determine the prevalence of 2 common disorders, 3β-hydroxy-Δ⁵-C₂₇-steroid dehydrogenase (3β-HSD) and Δ4 oxosteroid-5β-reductase (Δ⁴–3-oxoR) deficiencies and to describe current diagnostic and treatment strategies among different European paediatric hepatology centres. Liver samples of 17 infants with unfavorable ATZ outcome (Group I, n = 8, median age = 0.35 year) and good outcome (Group II, n = 9, 0.17 year), and 9 with biliary atresia (BA, median age = 0.17 year) as control, however, remain from identifying infected individuals to optimizing treatment and ensuring global access to antiviral therapy to all population groups, including children. Overall, patients and controls had comparable HRQoL. Patients reported significantly lower scores for school functioning (P = 0.004) as depicted by missing school or day care due to hospital visits. Eighty-five percent of parents reported extreme worry (7.0) when hearing their child's BA diagnosis. At 6 years after diagnosis, parents reported significantly less worry.