Risk of invasive fungal infections and Molecular diagnosis of Pneumocystis pneumonia in immunocompromised patients

Abstract

Introduction: Hepatitis B core (anti-HBc) antibody is an effective marker for occult Hepatitis B virus (HBV) infection and is an integral part of blood donor screening in many countries. This study was aimed to evaluate the prevalence of anti-HBc antibodies among voluntary blood donors in Thailand and its significance to reduce the risk of transfusion transmitted HBV infection.Methods: Nasopharyngeal swabs were obtained, Neisseria meningitidis was identified by standard methods, Polymerase Chain Reaction, and penicillin susceptibility was carried out. Multilocus Sequence Typing was performed as well. The study included 461 inmates. The overall carrier frequency was 10.41%, serogroups were isolated: B (20), C (17), Y (8) and nongroupable (3) 70.8% (34/48) of isolates showed some level of resistance to penicillin.

Conclusion: New advances in the understanding of the role of Leis mania RNA virus (LRV) as a prognostic factor, speciation methods and antimicrobial resistance testing and their limitations will be discussed.